At first blush it sounds like a complaint about insufficient disk space. Is your available disk space low?
It depends on your standards... I surely hope that 45gigs free isn't considered low these days. Damn spoiled computers... =)
Obviously, even in low-space situations, Inkscape shouldn't spew error messages continually or lock up; it should give you a warning so you
can
fix the situation. ;-)
I gave my comp a restart just in case and continued working and have not had that really bad issue since (however the first issue which I can continue working with continues to happen). But, it was definitely stuck in some kind of loop, because it just kept spewing those three messages repeatedly. I've never witnessed inkscape do anything of the sort before.
-Josh