I've just installed Inkscape for the first time (on Windows 10) and discovered the toolbars and buttons are so tiny they're unrecognizable and unusable. This is due to Inkscape not being "High DPI Aware" (see https://docs.microsoft.com/en-us/windows/desktop/hidpi/high-dpi-desktop-appl...).
The temporary solution is to right click the Inkscape icon, choose the "Properties" context menu item, then choose the "Compatibility" tab. Click on "Change High DPI Settings" and in the group box "High DPI scaling override" check the check box "Override high DPI scaling behavior." In the drop list select "System (Enhanced)". Click the "OK" button.
Now relaunch Inkscape and the compatibility mode will take effect.
Not sure how to file a bug on here but perhaps one of the developers can?