Zgzf Missing link found between brain, immune system -- with major disease implications PESHAWAR:Unidentified gunmen on Thursday kidnapped eight government employees in northwest region while they were heading to inspect an under <a href=https://www.valela.at>uggs hausschuhe</a> construction dam, officials said.The incident took place in Toi Khula area of the South Waziristan tribal district along the Afghan border where unidentified gunmen intercepted their vehicle and took them to an unknown location.Zafrul Islam, the top government official in South Waziristan, said project director of Chao Tangi small dam, two geologists and other technical staff of the dam were among those kidnapped at gunpoint.15 terrorists killed in Shawal air raids"Gunmen kidnapped th <a href=https://www.nbbalance.fr>newbalance 550</a> ese eight government employees when they were heading to the dam site," Islam told AFP.A second senior government official confirmed the abduction and told AFP that a search operation had been launched to locate the abductors.No group has yet claimed responsibility.South Waziristan is one of seven tribal districts which border Afghanistan and have been home to al Q <a href=https://www.inkwiz.se>boots kaufen</a> ae So vital is the p53 tumor suppressor gene in controlling cancer that its dysfunction is linked to more than half of human cancers. At the same time, the gene鈥檚 capacity for shutting down cell growth, even causing cells to commit suicide if necessary, is so absolute that it must be tightly regulated to maintain the optimal balance between protecting against cancer and permitting normal growth.Now, a study by scientists atThe Wistar Institute reveals new levels of subtlety in the body鈥檚 management of this all-important tumor suppressor gene and the protein it produces. The experiments show that, while the addition of a specific molecule at a particular site on the p53 protein prevents it from acting, the addition of a second copy of the same molecule at the same site reverses the effect, sending p53 into action. Further, removal o <a href=https://www.adidas-yeezys.com.mx>yeezy 350</a> f the second cop <a href=https://www.dunks.fr>dunk chaussure</a> y returns the protein to its repressed state.In addition to the implications for under <a href=https://www.dunks.fr>nike dunk high</a> standing the activity of the p53 gene, the findings also o